Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Aasdhppt (from a repository: Fri Apr 13 18:34:07 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)27
The number (and %) of the onco-proteins5 (18.52 %)
The number (and %) of the tumor suppressors1 (3.70 %)
Total number of binary PPIs (saturation %)65 (18.52 %)
The number (and %) of affected PPIs26 (40.00 %)
PPI diameter2
PPI radius1
The average degree of PPI4.000
Assortativity coefficient-0.4227
The network average Clustering coefficient0.628
The number (and %) of a zero Clustering coefficients4 (14.81 %)
The number (and %) of a zero Betweenness Centrality14 (51.85 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Aasdhppt
user protein260.086543.333ACPS (PF01648): 4'-phosphopantetheinyl transferase superfamily
Adss
interactor30.6670.667Adenylsucc_synt (PF00709): Adenylosuccinate synthetase
Babam1
interactor30.6670.667MPP6 (PF10175): M-phase phosphoprotein 6
VWA_2 (PF13519): von Willebrand factor type A domain
Capza2
interactor21.0000F-actin_cap_A (PF01267): F-actin capping protein alpha subunit
Ehd1
interactor41.0000EHD_N (PF16880): N-terminal EH-domain containing protein
Dynamin_N (PF00350): Dynamin family
Gtr1_RagA (PF04670): Gtr1/RagA G protein conserved region
Gp-FAR-1 (PF05823): Nematode fatty acid retinoid binding protein (Gp-FAR-1)
EF-hand_4 (PF12763): Cytoskeletal-regulatory complex EF hand
Ehd4
interactor50.6003.333EHD_N (PF16880): N-terminal EH-domain containing protein
Dynamin_N (PF00350): Dynamin family
GTP_EFTU (PF00009): Elongation factor Tu GTP binding domain
EF-hand_4 (PF12763): Cytoskeletal-regulatory complex EF hand
Hnrnpa1
interactor80.42910.667RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627): Nuclear factor hnRNPA1
Hnrnph1
oncogene40.8330.667RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RNPHF (PF08080): RNPHF zinc finger
LOC103732819
interactor31.0000F-box-like (PF12937): F-box-like
FBA (PF04300): F-box associated region
Mdfi
interactor200Herpes_LMP1 (PF05297): Herpesvirus latent membrane protein 1 (LMP1)
Herpes_UL56 (PF04534): Herpesvirus UL56 protein
MDFI (PF15316): MyoD family inhibitor
Mov10
interactor31.0000AAA_11 (PF13086): AAA domain
AAA_12 (PF13087): AAA domain
Mov10l1
interactor100S1-like (PF14444): S1-like
AAA_11 (PF13086): AAA domain
AAA_12 (PF13087): AAA domain
Mtmr14
interactor31.0000Y_phosphatase3 (PF13350): Tyrosine phosphatase family
Myotub-related (PF06602): Myotubularin-like phosphatase domain
Ntrk1
oncogene80.4769.667LRR_8 (PF13855): Leucine rich repeat
TPKR_C2 (PF16920): Tyrosine-protein kinase receptor C2 Ig-like domain
Ig_3 (PF13927): Immunoglobulin domain
I-set (PF07679): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714): Protein tyrosine kinase
Nxf1
interactor80.28614.000Tap-RNA_bind (PF09162): Tap, RNA-binding
LRR_8 (PF13855): Leucine rich repeat
NTF2 (PF02136): Nuclear transport factor 2 (NTF2) domain
TAP_C (PF03943): TAP C-terminal domain
Paxip1
interactor30.6670.667PTCB-BRCT (PF12738): twin BRCT domain
RTT107_BRCT_5 (PF16770): Regulator of Ty1 transposition protein 107 BRCT domain
CPSF100_C (PF13299): Cleavage and polyadenylation factor 2 C-terminal
LIG3_BRCT (PF16759): DNA ligase 3 BRCT domain
Exonuc_VII_L (PF02601): Exonuclease VII, large subunit
AIM3 (PF17096): Altered inheritance of mitochondria protein 3
BRCT (PF00533): BRCA1 C Terminus (BRCT) domain
BRCT_2 (PF16589): BRCT domain, a BRCA1 C-terminus domain
Plcg1
oncogene40.6671.667PH_12 (PF16457): Pleckstrin homology domain
PI-PLC-X (PF00388): Phosphatidylinositol-specific phospholipase C, X domain
PH (PF00169): PH domain
SH2 (PF00017): SH2 domain
SH3_1 (PF00018): SH3 domain
PI-PLC-Y (PF00387): Phosphatidylinositol-specific phospholipase C, Y domain
C2 (PF00168): C2 domain
Ppp1r3c
interactor21.0000CBM53 (PF16760): Starch/carbohydrate-binding module (family 53)
CBM_21 (PF03370): Carbohydrate/starch-binding module (family 21)
Sgta
interactor50.4005.667SGTA_dimer (PF16546): Homodimerisation domain of SGTA
TPR_11 (PF13414): TPR repeat
TPR_1 (PF00515): Tetratricopeptide repeat
TOM20_plant (PF06552): Plant specific mitochondrial import receptor subunit TOM20
XPC-binding (PF09280): XPC-binding domain
Siah1
tumor suppressor31.0000CBM_19 (PF03427): Carbohydrate binding domain (family 19)
Sina (PF03145): Seven in absentia protein family
Stil
oncogene100STIL_N (PF15253): SCL-interrupting locus protein N-terminus
Traf2
interactor31.0000zf-C3HC4 (PF00097): Zinc finger, C3HC4 type (RING finger)
Fer4_3 (PF12798): 4Fe-4S binding domain
zf-C3HC4_5 (PF17121): Zinc finger, C3HC4 type (RING finger)
zf-TRAF (PF02176): TRAF-type zinc finger
TRAF_BIRC3_bd (PF16673): TNF receptor-associated factor BIRC3 binding domain
DUF1664 (PF07889): Protein of unknown function (DUF1664)
MATH (PF00917): MATH domain
Trappc4
interactor200Sybindin (PF04099): Sybindin-like family
Ube2d2
oncogene31.0000UQ_con (PF00179): Ubiquitin-conjugating enzyme
Umps
interactor40.5002.333Pribosyltran (PF00156): Phosphoribosyl transferase domain
OMPdecase (PF00215): Orotidine 5'-phosphate decarboxylase / HUMPS family
Usp22
interactor31.0000DUF2769 (PF10967): Protein of unknown function (DUF2769)
zf-UBP (PF02148): Zn-finger in ubiquitin-hydrolases and other protein
UCH (PF00443): Ubiquitin carboxyl-terminal hydrolase
Zc3hc1
interactor30.6670.667zf-C3HC (PF07967): C3HC zinc finger-like
Rsm1 (PF08600): Rsm1-like
Yippee-Mis18 (PF03226): Yippee zinc-binding/DNA-binding /Mis18, centromere assembly

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