Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Aar2 (from a repository: Thu Apr 12 01:58:24 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)21
The number (and %) of the onco-proteins1 (4.76 %)
The number (and %) of the tumor suppressors1 (4.76 %)
Total number of binary PPIs (saturation %)66 (31.43 %)
The number (and %) of affected PPIs20 (30.30 %)
PPI diameter2
PPI radius1
The average degree of PPI5.714
Assortativity coefficient-0.3433
The network average Clustering coefficient0.550
The number (and %) of a zero Clustering coefficients5 (23.81 %)
The number (and %) of a zero Betweenness Centrality8 (38.10 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Aar2
user protein200.211241.586AAR2 (PF05282): AAR2 protein
Cenpj
interactor100CorA (PF01544): CorA-like Mg2+ transporter protein
Rota_VP2 (PF05087): Rotavirus VP2 protein
DUF4972 (PF16342): Domain of unknown function (DUF4972)
DUF848 (PF05852): Gammaherpesvirus protein of unknown function (DUF848)
Tho2 (PF11262): Transcription factor/nuclear export subunit protein 2
IncA (PF04156): IncA protein
Tcp10_C (PF07202): T-complex protein 10 C-terminus
Cul3
interactor80.47610.000Cullin (PF00888): Cullin family
WAC_Acf1_DNA_bd (PF10537): ATP-utilising chromatin assembly and remodelling N-terminal
Cullin_Nedd8 (PF10557): Cullin protein neddylation domain
Ddx23
interactor60.9330.286FUSC (PF04632): Fusaric acid resistance protein family
DUF4569 (PF15133): Domain of unknown function (DUF4569)
DUF3698 (PF12479): Protein of unknown function (DUF3698)
DEAD (PF00270): DEAD/DEAH box helicase
Helicase_C (PF00271): Helicase conserved C-terminal domain
Eapp
interactor80.7862.467DTHCT (PF08070): DTHCT (NUC029) region
Eapp_C (PF10238): E2F-associated phosphoprotein
Ecd
interactor80.6796.852SGT1 (PF07093): SGT1 protein
Eftud2
interactor100.6676.286EFTUD2 (PF16004): 116 kDa U5 small nuclear ribonucleoprotein component N-terminus
GTP_EFTU (PF00009): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144): Elongation factor Tu domain 2
EFG_II (PF14492): Elongation Factor G, domain II
EFG_IV (PF03764): Elongation factor G, domain IV
EFG_C (PF00679): Elongation factor G C-terminus
Ghdc
interactor100GH3 (PF03321): GH3 auxin-responsive promoter
Gja5
interactor100Connexin (PF00029): Connexin
Connexin40_C (PF16791): Connexin 40 C-terminal domain
Kiaa1143
interactor51.0000DUF4604 (PF15377): Domain of unknown function (DUF4604)
Klhl36
interactor21.0000BTB (PF00651): BTB/POZ domain
BACK (PF07707): BTB And C-terminal Kelch
Kelch_6 (PF13964): Kelch motif
Kelch_1 (PF01344): Kelch motif
Ncdn
interactor30.6670.667Neurochondrin (PF05536): Neurochondrin
Prpf8
oncogene120.60013.252PRO8NT (PF08082): PRO8NT (NUC069), PrP8 N-terminal domain
PROCN (PF08083): PROCN (NUC071) domain
RRM_4 (PF10598): RNA recognition motif of the spliceosomal PrP8
U5_2-snRNA_bdg (PF10597): U5-snRNA binding site 2 of PrP8
U6-snRNA_bdg (PF10596): U6-snRNA interacting domain of PrP8
PRP8_domainIV (PF12134): PRP8 domain IV core
JAB (PF01398): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
PROCT (PF08084): PROCT (NUC072) domain
Ptpn9
interactor200CRAL_TRIO_N (PF03765): CRAL/TRIO, N-terminal domain
CRAL_TRIO (PF00650): CRAL/TRIO domain
DUF4140 (PF13600): N-terminal domain of unknown function (DUF4140)
Y_phosphatase (PF00102): Protein-tyrosine phosphatase
Slc7a6os
interactor100Iwr1 (PF08574): Transcription factor Iwr1
DNA_pol_phi (PF04931): DNA polymerase phi
Snrnp200
interactor120.60012.252DEAD (PF00270): DEAD/DEAH box helicase
Helicase_C (PF00271): Helicase conserved C-terminal domain
Sec63 (PF02889): Sec63 Brl domain
DUF603 (PF04645): Protein of unknown function, DUF603
Snrnp40
interactor70.8571.067WD40 (PF00400): WD domain, G-beta repeat
Tssc4
tumor suppressor70.9050.619TSSC4 (PF15264): Tumour suppressing sub-chromosomal transferable candidate 4
Ttc5
interactor21.0000V-SNARE (PF05008): Vesicle transport v-SNARE protein N-terminus
TPR_11 (PF13414): TPR repeat
TPR_2 (PF07719): Tetratricopeptide repeat
DUF945 (PF06097): Bacterial protein of unknown function (DUF945)
TTC5_OB (PF16669): Tetratricopeptide repeat protein 5 OB fold domain
Ubc
interactor60.5003.667ubiquitin (PF00240): Ubiquitin family
Ubr4
interactor40.6671.000FAM176 (PF14851): FAM176 family
CAP_N (PF01213): Adenylate cyclase associated (CAP) N terminal
zf-UBR (PF02207): Putative zinc finger in N-recognin (UBR box)
Pheromone (PF08015): Fungal mating-type pheromone
Ribosomal_60s (PF00428): 60s Acidic ribosomal protein
AP3D1 (PF06375): AP-3 complex subunit delta-1
RecR (PF02132): RecR protein
DZR (PF12773): Double zinc ribbon
E3_UbLigase_R4 (PF13764): E3 ubiquitin-protein ligase UBR4

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