Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Aamp (from a repository: Fri Apr 13 07:26:06 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)28
The number (and %) of the onco-proteins3 (10.71 %)
The number (and %) of the tumor suppressors4 (14.29 %)
Total number of binary PPIs (saturation %)56 (14.81 %)
The number (and %) of affected PPIs27 (48.21 %)
PPI diameter2
PPI radius1
The average degree of PPI3.214
Assortativity coefficient-0.5326
The network average Clustering coefficient0.525
The number (and %) of a zero Clustering coefficients10 (35.71 %)
The number (and %) of a zero Betweenness Centrality22 (78.57 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Aamp
user protein270.051641.000WD40 (PF00400): WD domain, G-beta repeat
PQQ (PF01011): PQQ enzyme repeat
ANAPC4_WD40 (PF12894): Anaphase-promoting complex subunit 4 WD40 domain
Ace2
interactor200Peptidase_M2 (PF01401): Angiotensin-converting enzyme
Collectrin (PF16959): Renal amino acid transporter
Glycophorin_A (PF01102): Glycophorin A
Aen
interactor100RNase_T (PF00929): Exonuclease
Asah1
interactor100NAAA-beta (PF15508): beta subunit of N-acylethanolamine-hydrolyzing acid amidase
CBAH (PF02275): Linear amide C-N hydrolases, choloylglycine hydrolase family
Atoh1
interactor100HLH (PF00010): Helix-loop-helix DNA-binding domain
Bhlhe40
interactor200HLH (PF00010): Helix-loop-helix DNA-binding domain
Hairy_orange (PF07527): Hairy Orange
Dhps
interactor51.0000DS (PF01916): Deoxyhypusine synthase
Dicer1
oncogene, tumor suppressor200DEAD (PF00270): DEAD/DEAH box helicase
PBP1_TM (PF14812): Transmembrane domain of transglycosylase PBP1 at N-terminal
CENP-B_dimeris (PF09026): Centromere protein B dimerisation domain
Helicase_C (PF00271): Helicase conserved C-terminal domain
Dicer_dimer (PF03368): Dicer dimerisation domain
ANAPC15 (PF15243): Anaphase-promoting complex subunit 15
PAZ (PF02170): PAZ domain
Ribonuclease_3 (PF00636): Ribonuclease III domain
dsrm (PF00035): Double-stranded RNA binding motif
Gabarapl2
interactor30.6671.000Atg8 (PF02991): Autophagy protein Atg8 ubiquitin like
Hsf1
heat shock51.0000HSF_DNA-bind (PF00447): HSF-type DNA-binding
DUF247 (PF03140): Plant protein of unknown function
Vert_HS_TF (PF06546): Vertebrate heat shock transcription factor
Inpp5k
oncogene21.0000Exo_endo_phos (PF03372): Endonuclease/Exonuclease/phosphatase family
CALCOCO1 (PF07888): Calcium binding and coiled-coil domain (CALCOCO1) like
LOC103748852
interactor50.5003.000Recep_L_domain (PF01030): Receptor L domain
Furin-like (PF00757): Furin-like cysteine rich region
GF_recep_IV (PF14843): Growth factor receptor domain IV
Map1lc3b
interactor21.0000Atg8 (PF02991): Autophagy protein Atg8 ubiquitin like
Paxip1
interactor40.5003.000PTCB-BRCT (PF12738): twin BRCT domain
RTT107_BRCT_5 (PF16770): Regulator of Ty1 transposition protein 107 BRCT domain
CPSF100_C (PF13299): Cleavage and polyadenylation factor 2 C-terminal
LIG3_BRCT (PF16759): DNA ligase 3 BRCT domain
Exonuc_VII_L (PF02601): Exonuclease VII, large subunit
AIM3 (PF17096): Altered inheritance of mitochondria protein 3
BRCT (PF00533): BRCA1 C Terminus (BRCT) domain
BRCT_2 (PF16589): BRCT domain, a BRCA1 C-terminus domain
Pdcd4
oncogene, tumor suppressor21.0000Adhes-Ig_like (PF09085): Adhesion molecule, immunoglobulin-like
HABP4_PAI-RBP1 (PF04774): Hyaluronan / mRNA binding family
MA3 (PF02847): MA3 domain
Plin3
interactor51.0000Perilipin (PF03036): Perilipin family
Ppp2r2d
interactor100WD40 (PF00400): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894): Anaphase-promoting complex subunit 4 WD40 domain
Ptf1a
interactor100HLH (PF00010): Helix-loop-helix DNA-binding domain
Ptpru
oncogene21.0000MAM (PF00629): MAM domain, meprin/A5/mu
fn3 (PF00041): Fibronectin type III domain
PsbX (PF06596): Photosystem II reaction centre X protein (PsbX)
Y_phosphatase (PF00102): Protein-tyrosine phosphatase
Rpl10
oncogene, tumor suppressor100Ribosomal_L16 (PF00252): Ribosomal protein L16p/L10e
Srp9
interactor50.7003.000SRP9-21 (PF05486): Signal recognition particle 9 kDa protein (SRP9)
Tbxa2r
interactor2007tm_1 (PF00001): 7 transmembrane receptor (rhodopsin family)
Tcf25
interactor21.0000Tcf25 (PF04910): Transcriptional repressor TCF25
Tk1
oncogene31.0000TK (PF00265): Thymidine kinase
Tp53bp1
oncogene, tumor suppressor21.0000DUF2052 (PF09747): Coiled-coil domain containing protein (DUF2052)
53-BP1_Tudor (PF09038): Tumour suppressor p53-binding protein-1 Tudor
RTT107_BRCT_5 (PF16770): Regulator of Ty1 transposition protein 107 BRCT domain
BRCT (PF00533): BRCA1 C Terminus (BRCT) domain
Vps52
interactor31.0000Vps52 (PF04129): Vps52 / Sac2 family
Sec3_C (PF09763): Exocyst complex component Sec3
COG5 (PF10392): Golgi transport complex subunit 5
Wnk1
interactor31.0000TFIIA (PF03153): Transcription factor IIA, alpha/beta subunit
DUF2360 (PF10152): Predicted coiled-coil domain-containing protein (DUF2360)
Pkinase (PF00069): Protein kinase domain
OSR1_C (PF12202): Oxidative-stress-responsive kinase 1 C terminal
SynMuv_product (PF06047): Ras-induced vulval development antagonist
TraV (PF09676): Type IV conjugative transfer system lipoprotein (TraV)
Xpo1
interactor70.28615.000IBN_N (PF03810): Importin-beta N-terminal domain
Xpo1 (PF08389): Exportin 1-like protein
Vac14_Fab1_bd (PF12755): Vacuolar 14 Fab1-binding region
Hydrolase_3 (PF08282): haloacid dehalogenase-like hydrolase
CRM1_C (PF08767): CRM1 C terminal

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