Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Aagab (from a repository: Sat Apr 21 16:22:41 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)19
The number (and %) of the onco-proteins1 (5.26 %)
The number (and %) of the tumor suppressors1 (5.26 %)
Total number of binary PPIs (saturation %)36 (21.05 %)
The number (and %) of affected PPIs18 (50.00 %)
PPI diameter2
PPI radius1
The average degree of PPI3.579
Assortativity coefficient-0.4913
The network average Clustering coefficient0.509
The number (and %) of a zero Clustering coefficients6 (31.58 %)
The number (and %) of a zero Betweenness Centrality12 (63.16 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Aagab
user protein180.105245.333Ras (PF00071): Ras family
Adaptin_binding (PF10199): Alpha and gamma adaptin binding protein p34
Ap1g1
interactor40.6671.667Adaptin_N (PF01602): Adaptin N terminal region
Alpha_adaptinC2 (PF02883): Adaptin C-terminal domain
Ap1g2
interactor31.0000Adaptin_N (PF01602): Adaptin N terminal region
Alpha_adaptinC2 (PF02883): Adaptin C-terminal domain
Ap1s2
interactor50.7002.000Clat_adaptor_s (PF01217): Clathrin adaptor complex small chain
Ap1s3
interactor100Clat_adaptor_s (PF01217): Clathrin adaptor complex small chain
DUF3387 (PF11867): Domain of unknown function (DUF3387)
Ap2a1
interactor40.6671.667Adaptin_N (PF01602): Adaptin N terminal region
HEAT_2 (PF13646): HEAT repeats
Alpha_adaptinC2 (PF02883): Adaptin C-terminal domain
Alpha_adaptin_C (PF02296): Alpha adaptin AP2, C-terminal domain
Ap2a2
interactor31.0000Adaptin_N (PF01602): Adaptin N terminal region
HEAT_2 (PF13646): HEAT repeats
Alpha_adaptinC2 (PF02883): Adaptin C-terminal domain
Alpha_adaptin_C (PF02296): Alpha adaptin AP2, C-terminal domain
Ap2s1
interactor50.5004.667Clat_adaptor_s (PF01217): Clathrin adaptor complex small chain
Apba2
interactor100PID (PF00640): Phosphotyrosine interaction domain (PTB/PID)
PDZ (PF00595): PDZ domain (Also known as DHR or GLGF)
Asah1
interactor100NAAA-beta (PF15508): beta subunit of N-acylethanolamine-hydrolyzing acid amidase
CBAH (PF02275): Linear amide C-N hydrolases, choloylglycine hydrolase family
Ccdc32
interactor21.0000CCDC32 (PF14989): Coiled-coil domain containing 32
Elavl1
oncogene50.6672.000RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Fam177a1
interactor100FAM177 (PF14774): FAM177 family
Fbxl14
interactor100F-box-like (PF12937): F-box-like
LRR_4 (PF12799): Leucine Rich repeats (2 copies)
Ste50p-SAM (PF09235): Ste50p, sterile alpha motif
LRR_6 (PF13516): Leucine Rich repeat
Heatr1
interactor100U3snoRNP10 (PF12397): U3 small nucleolar RNA-associated protein 10
RTP1_C1 (PF10363): Required for nuclear transport of RNA pol II C-terminus 1
HEAT (PF02985): HEAT repeat
Cnd1 (PF12717): non-SMC mitotic condensation complex subunit 1
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
BP28CT (PF08146): BP28CT (NUC211) domain
LOC103726401
interactor21.0000eIF-3c_N (PF05470): Eukaryotic translation initiation factor 3 subunit 8 N-terminus
PCI (PF01399): PCI domain
Stxbp3
interactor21.0000Sec1 (PF00995): Sec1 family
Tp53
tumor suppressor31.0000P53_TAD (PF08563): P53 transactivation motif
P53 (PF00870): P53 DNA-binding domain
P53_tetramer (PF07710): P53 tetramerisation motif
Xpo1
interactor80.35716.667IBN_N (PF03810): Importin-beta N-terminal domain
Xpo1 (PF08389): Exportin 1-like protein
Vac14_Fab1_bd (PF12755): Vacuolar 14 Fab1-binding region
Hydrolase_3 (PF08282): haloacid dehalogenase-like hydrolase
CRM1_C (PF08767): CRM1 C terminal

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