Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Aaas (from a repository: Fri Apr 13 16:06:46 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)18
The number (and %) of the onco-proteins2 (11.11 %)
The number (and %) of the tumor suppressors1 (5.56 %)
Total number of binary PPIs (saturation %)51 (33.33 %)
The number (and %) of affected PPIs17 (33.33 %)
PPI diameter2
PPI radius1
The average degree of PPI4.889
Assortativity coefficient-0.4140
The network average Clustering coefficient0.495
The number (and %) of a zero Clustering coefficients6 (33.33 %)
The number (and %) of a zero Betweenness Centrality9 (50.00 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Aaas
user protein170.199186.152ANAPC4_WD40 (PF12894): Anaphase-promoting complex subunit 4 WD40 domain
WD40 (PF00400): WD domain, G-beta repeat
PD40 (PF07676): WD40-like Beta Propeller Repeat
Ctdnep1
interactor100NIF (PF03031): NLI interacting factor-like phosphatase
Cul7
interactor41.0000Cul7 (PF11515): Mouse development and cellular proliferation protein Cullin-7
ANAPC10 (PF03256): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888): Cullin family
Cullin_Nedd8 (PF10557): Cullin protein neddylation domain
Efnb2
interactor100Ephrin (PF00812): Ephrin
TMEM132D_C (PF15706): Mature oligodendrocyte transmembrane protein, TMEM132D, C-term
Isg15
tumor suppressor100ubiquitin (PF00240): Ubiquitin family
Kpnb1
interactor100.55610.367IBN_N (PF03810): Importin-beta N-terminal domain
HEAT_EZ (PF13513): HEAT-like repeat
V-ATPase_H_C (PF11698): V-ATPase subunit H
Arm (PF00514): Armadillo/beta-catenin-like repeat
Cnd1 (PF12717): non-SMC mitotic condensation complex subunit 1
HEAT (PF02985): HEAT repeat
CLASP_N (PF12348): CLASP N terminal
LOC103748852
interactor60.8000.686Recep_L_domain (PF01030): Receptor L domain
Furin-like (PF00757): Furin-like cysteine rich region
GF_recep_IV (PF14843): Growth factor receptor domain IV
Ntrk1
oncogene60.8000.686LRR_8 (PF13855): Leucine rich repeat
TPKR_C2 (PF16920): Tyrosine-protein kinase receptor C2 Ig-like domain
Ig_3 (PF13927): Immunoglobulin domain
I-set (PF07679): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714): Protein tyrosine kinase
Nup107
interactor80.7143.752Nup84_Nup100 (PF04121): Nuclear pore protein 84 / 107
Nup153
interactor90.7143.752Nup153 (PF08604): Nucleoporin Nup153-like
zf-RanBP (PF00641): Zn-finger in Ran binding protein and others
Nup_retrotrp_bd (PF10599): Retro-transposon transporting motif
Nucleoporin_FG (PF13634): Nucleoporin FG repeat region
Obsl1
interactor70.7332.619I-set (PF07679): Immunoglobulin I-set domain
Herpes_gE (PF02480): Alphaherpesvirus glycoprotein E
fn3 (PF00041): Fibronectin type III domain
Ig_3 (PF13927): Immunoglobulin domain
BiPBP_C (PF06832): Penicillin-Binding Protein C-terminus Family
Ig_4 (PF16680): T-cell surface glycoprotein CD3 delta chain
Popdc2
interactor100Popeye (PF04831): Popeye protein conserved region
Rel
oncogene21.0000RHD_DNA_bind (PF00554): Rel homology DNA-binding domain
RHD_dimer (PF16179): Rel homology dimerisation domain
Seh1l
interactor51.0000WD40 (PF00400): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894): Anaphase-promoting complex subunit 4 WD40 domain
Ge1_WD40 (PF16529): WD40 region of Ge1, enhancer of mRNA-decapping protein
Tctn2
interactor100DUF1619 (PF07773): Protein of unknown function (DUF1619)
Tctn3
interactor100DUF1619 (PF07773): Protein of unknown function (DUF1619)
Ube2i
interactor70.8670.786UQ_con (PF00179): Ubiquitin-conjugating enzyme
Xpo1
interactor80.5369.200IBN_N (PF03810): Importin-beta N-terminal domain
Xpo1 (PF08389): Exportin 1-like protein
Vac14_Fab1_bd (PF12755): Vacuolar 14 Fab1-binding region
Hydrolase_3 (PF08282): haloacid dehalogenase-like hydrolase
CRM1_C (PF08767): CRM1 C terminal

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