Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) A2ml1 (from a repository: Wed Apr 11 12:06:25 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)18
The number (and %) of the onco-proteins0 (0.00 %)
The number (and %) of the tumor suppressors1 (5.56 %)
Total number of binary PPIs (saturation %)25 (16.34 %)
The number (and %) of affected PPIs17 (68.00 %)
PPI diameter2
PPI radius1
The average degree of PPI2.000
Assortativity coefficient-0.5423
The network average Clustering coefficient0.112
The number (and %) of a zero Clustering coefficients15 (83.33 %)
The number (and %) of a zero Betweenness Centrality17 (94.44 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
A2ml1
user protein170.007270.000A2M_N (PF01835): MG2 domain
A2M_N_2 (PF07703): Alpha-2-macroglobulin family N-terminal region
A2M (PF00207): Alpha-2-macroglobulin family
SVA (PF05326): Seminal vesicle autoantigen (SVA)
Thiol-ester_cl (PF10569): Alpha-macro-globulin thiol-ester bond-forming region
A2M_comp (PF07678): A-macroglobulin complement component
A2M_recep (PF07677): A-macroglobulin receptor
Acad9
interactor100Acyl-CoA_dh_N (PF02771): Acyl-CoA dehydrogenase, N-terminal domain
Acyl-CoA_dh_M (PF02770): Acyl-CoA dehydrogenase, middle domain
Acyl-CoA_dh_1 (PF00441): Acyl-CoA dehydrogenase, C-terminal domain
Ccnyl1
interactor100Cyclin_N (PF00134): Cyclin, N-terminal domain
Dusp19
interactor200DSPc (PF00782): Dual specificity phosphatase, catalytic domain
Foxd2
interactor200Forkhead (PF00250): Forkhead domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
Peptidase_M66 (PF10462): Peptidase M66
Foxh1
interactor100Forkhead (PF00250): Forkhead domain
Fth1
interactor100Ferritin (PF00210): Ferritin-like domain
Gmcl1
interactor200BTB (PF00651): BTB/POZ domain
BACK (PF07707): BTB And C-terminal Kelch
Hnrnpa1
interactor31.0000RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627): Nuclear factor hnRNPA1
L2hgdh
interactor100DAO (PF01266): FAD dependent oxidoreductase
LOC103731120
interactor200UDPGT (PF00201): UDP-glucoronosyl and UDP-glucosyl transferase
Nppa
interactor100ANP (PF00212): Atrial natriuretic peptide
Pi4ka
interactor100Serglycin (PF04360): Serglycin
Ribosomal_L18_c (PF14204): Ribosomal L18 C-terminal region
Ipi1_N (PF12333): Rix1 complex component involved in 60S ribosome maturation
PI3Ka (PF00613): Phosphoinositide 3-kinase family, accessory domain (PIK domain)
PI3_PI4_kinase (PF00454): Phosphatidylinositol 3- and 4-kinase
Slc39a11
interactor100Zip (PF02535): ZIP Zinc transporter
Tbc1d22b
interactor100DUF4502 (PF14950): Domain of unknown function (DUF4502)
MIF4G (PF02854): MIF4G domain
RabGAP-TBC (PF00566): Rab-GTPase-TBC domain
Thra
oncogene, tumor suppressor200C1_2 (PF03107): C1 domain
zf-C4 (PF00105): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104): Ligand-binding domain of nuclear hormone receptor
Tox4
interactor31.0000YABBY (PF04690): YABBY protein
HMG_box (PF00505): HMG (high mobility group) box
FAP (PF07174): Fibronectin-attachment protein (FAP)
zf-C4H2 (PF10146): Zinc finger-containing protein
Extensin_2 (PF04554): Extensin-like region
Zfand4
interactor100ubiquitin (PF00240): Ubiquitin family
zf-AN1 (PF01428): AN1-like Zinc finger

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