Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) A1bg (from a repository: Sat Apr 14 14:18:58 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)19
The number (and %) of the onco-proteins1 (5.26 %)
The number (and %) of the tumor suppressors2 (10.53 %)
Total number of binary PPIs (saturation %)30 (17.54 %)
The number (and %) of affected PPIs18 (60.00 %)
PPI diameter2
PPI radius1
The average degree of PPI2.421
Assortativity coefficient-0.3246
The network average Clustering coefficient0.326
The number (and %) of a zero Clustering coefficients11 (57.89 %)
The number (and %) of a zero Betweenness Centrality16 (84.21 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
A1bg
user protein180.033292.000Ig_2 (PF13895): Immunoglobulin domain
Abcc6
interactor100ABC_membrane (PF00664): ABC transporter transmembrane region
ABC_tran (PF00005): ABC transporter
SMC_N (PF02463): RecF/RecN/SMC N terminal domain
Anxa7
tumor suppressor100Annexin (PF00191): Annexin
Cdkn1a
oncogene, tumor suppressor30.6671.000CDI (PF02234): Cyclin-dependent kinase inhibitor
Crisp1
interactor100CAP (PF00188): Cysteine-rich secretory protein family
Crisp (PF08562): Crisp
Grb7
interactor100RA (PF00788): Ras association (RalGDS/AF-6) domain
PH (PF00169): PH domain
BPS (PF08947): BPS (Between PH and SH2)
SH2 (PF00017): SH2 domain
Prdx4
interactor200AhpC-TSA (PF00578): AhpC/TSA family
1-cysPrx_C (PF10417): C-terminal domain of 1-Cys peroxiredoxin
Psme4
interactor100BLM10_mid (PF16507): Proteasome-substrate-size regulator, mid region
HEAT (PF02985): HEAT repeat
DUF3437 (PF11919): Domain of unknown function (DUF3437)
Rnf123
interactor21.0000SPRY (PF00622): SPRY domain
DUF1265 (PF06887): Protein of unknown function (DUF1265)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
Setd7
interactor200SR-25 (PF10500): Nuclear RNA-splicing-associated protein
MORN (PF02493): MORN repeat
MORN_2 (PF07661): MORN repeat variant
SET (PF00856): SET domain
Shmt2
interactor21.0000SHMT (PF00464): Serine hydroxymethyltransferase
Smn1
interactor200SMN (PF06003): Survival motor neuron protein (SMN)
Snca
interactor200Synuclein (PF01387): Synuclein
Tk1
oncogene31.0000TK (PF00265): Thymidine kinase
Ubac1
interactor21.0000Rad60-SLD_2 (PF13881): Ubiquitin-2 like Rad60 SUMO-like
HEAT_2 (PF13646): HEAT repeats
UBA (PF00627): UBA/TS-N domain
Ubr4
interactor40.5003.000FAM176 (PF14851): FAM176 family
CAP_N (PF01213): Adenylate cyclase associated (CAP) N terminal
zf-UBR (PF02207): Putative zinc finger in N-recognin (UBR box)
Pheromone (PF08015): Fungal mating-type pheromone
Ribosomal_60s (PF00428): 60s Acidic ribosomal protein
AP3D1 (PF06375): AP-3 complex subunit delta-1
RecR (PF02132): RecR protein
DZR (PF12773): Double zinc ribbon
E3_UbLigase_R4 (PF13764): E3 ubiquitin-protein ligase UBR4
Ubxn1
interactor31.0000UBA (PF00627): UBA/TS-N domain
eIF3_subunit (PF08597): Translation initiation factor eIF3 subunit
Selenoprotein_S (PF06936): Selenoprotein S (SelS)
UBX (PF00789): UBX domain
Wdr62
interactor200WD40 (PF00400): WD domain, G-beta repeat
eIF2A (PF08662): Eukaryotic translation initiation factor eIF2A
ANAPC4_WD40 (PF12894): Anaphase-promoting complex subunit 4 WD40 domain
Zbtb40
interactor100BTB (PF00651): BTB/POZ domain
DUF2360 (PF10152): Predicted coiled-coil domain-containing protein (DUF2360)
PHD (PF00628): PHD-finger
zf-H2C2_2 (PF13465): Zinc-finger double domain
zf-C2H2 (PF00096): Zinc finger, C2H2 type
zinc_ribbon_15 (PF17032): zinc-ribbon family
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-Di19 (PF05605): Drought induced 19 protein (Di19), zinc-binding
FOXP-CC (PF16159): FOXP coiled-coil domain

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